Abstract Background Tumor repopulation is a major cause of radiotherapy failure.Previous investigations highlighted that dying tumor cells played vital roles in tumor repopulation through promoting proliferation of the residual tumor repopulating cells (TRCs).However, TRCs also suffer DNA damage after radiotherapy, and might undergo mitotic catastr
Influence degree of constrained conditions on overhaul of apartment buildings
When carrying Masters of the Universe out the repair and construction work in the apartment buildings and when creating an organizational and technological model, it is necessary to take into account and analyze all the parameters that influence on these works to optimize the time and financial costs.The complicating conditions of the construction
CircPRMT5 promotes progression of osteosarcoma by recruiting CNBP to regulate the translation and stability of CDK6 mRNA.
Research has demonstrated that circular RNAs (circRNAs) exert critical functions in the occurrence and progression of numerous malignant tumors.CircPRMT5 was Masters of the Universe recently reported to be involved in the pathogenesis of cancers.However, the potential role of circPRMT5 in osteosarcoma needs further investigation.In present study, o
MVA vector expression of SARS-CoV-2 spike protein and protection of adult Syrian hamsters against SARS-CoV-2 challenge
Abstract Numerous vaccine candidates against SARS-CoV-2, the causative agent of the COVID-19 pandemic, are under development.The majority of vaccine candidates to date are designed to induce immune responses against the viral spike (S) protein, although different forms of S antigen have been incorporated.To evaluate the yield and immunogenicity of
Notas introdutórias sobre gestão escolar na perspectiva da pedagogia histórico-crítica
Esse texto busca apresentar, de forma introdutória, algumas reflexões de caráter teórico acerca da gestão da escola fundamentando-se nos pressupostos da Pedagogia histórico-crítica (PHC) nos quais nossas ações enquanto gestores se sustentaram.Não se trata, portanto, de um relato de experiência mas sim de um esforço de contribuir para a